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CELL GRAND CLINIC
CELL GRAND CLINIC

Best Stem Cell & Regenerative Medicine Clinic in Japan

Certified by the Ministry of Health across 13 specialized treatments

  • Chronic Pain
    Treatment of Chronic Pain Using Autologous Adipose-Derived Stem Cells Type 2 plan number
    PB5240089
  • Joint Disorders
    Treatment of Osteoarthritis Using Autologous Adipose-Derived Stem CellsType 2 plan number
    PB5240090
  • Diabetes
    Treatment of Diabetes Mellitus and Prediabetes Using Autologous Adipose-Derived Stem CellsType 2 plan number
    PB5250050
  • Arteriosclerosis
    Treatment of Arteriosclerosis Using Autologous Adipose-Derived Stem Cells Type 2 plan number
    PB5250050
  • Age Reversal &
Vitality
    Treatment of Frailty and Pre-frailty Using Autologous Adipose-Derived Stem CellsType 2 plan number
    PB5250049
  • Hair Loss 
(Alopecia)
    Treatment of Androgenetic Alopecia Using Autologous Adipose-Derived Stem CellsType 2 plan number
    PB5250047
  • Erectile
Dysfunction (ED)
    Treatment of Erectile Dysfunction (ED) Using Autologous Adipose-Derived Stem CellsType 2 plan number
    PB5250048
  • Knee Joint
Regeneration
    Platelet-Rich Plasma (PRP) Intra-Articular Injection Therapy for OsteoarthritisType 2 plan number
    PB5250010
  • Dermal
Regeneration
    Skin Regeneration Therapy Using Autologous Cultured Dermal FibroblastsType 2 plan number
    PB5250028
  • Skin
Rejuvenation
    Treatment of Age-Related Skin Changes Such as Wrinkles and Sagging Using Autologous Adipose-Derived Stem CellsType 2 plan number
    PB5250055
  • Skin
Rejuvenation
    Skin Regeneration Therapy Using Platelet-Rich Plasma (PRP) Type 3 plan number
    PC5250008
  • Hair Follicle
Regeneration
    Hair Tissue Regeneration Therapy using Platelet-Rich
    Plasma
    Type 3 plan number
    PC5250007
  • Cancer
Prevention
    NK Cell ImmunotherapyType 3 plan number
    PC5250041

Advanced Regenerative Medicine Clinic

Science-based Personalized Regenerative Solutions

  • Autologous Adipose-Derived Stem Cell Therapy
  • Fibroblast Therapy
  • NK Cell Immunotherapy
  • Stem Cell Supernatant Therapy
  • PRP (Platelet-Rich Plasma) Therapy
  • NMN Longevity Therapy
  • Comprehensive Cancer Screening

Your Best Years Are
Ahead of You

Reclaim your health, restore your vitality, and rediscover life’s possibilities

The Power of Your Own CellsRegenerative medicine harnesses your body’s natural healing power—a revolutionary approach beyond conventional medication or surgery. By working with your body rather than against it, regenerative therapy targets root causes, minimizes systemic burden, and offers hope for chronic or treatment-resistant conditions.

Quality MattersYour cells are living entities whose quality determines your results. Like a master chef selecting premium ingredients, we meticulously cultivate and manage every cell through rigorous safety protocols, uncompromising quality control, and complete transparency.

Your Healthspan, ExtendedBy activating your body’s regenerative power, we help you move freely,
work energetically, and enjoy life fully—adding healthy, vibrant years to your lifespan.

M.D., Ph.D. | Medical Director若林雄一
Yuichi Wakabayashi

Yuichi Wakabayashi

Director’s Profile

  • International Recognition
    —Published in leading U.S. and international journals
  • Clinical Excellence
    —Board-certified in multiple specialties
  • Research Pioneer
    —First-author breakthrough studies in neuroscience
  • Patient-Centered
    —Fluent in English, dedicated to personalized care
  • Academic Leader
    —NIH research fellow, university lecturer

Clinical Expertise

  • Advanced Regenerative Therapies
  • Preventive & Longevity Medicine
  • Age-Reversal Treatments
  • Aesthetic Cellular Rejuvenation

Main Professional Affiliations and Qualifications

  • Board-Certified Specialist, American Academy of Regenerative Medicine
  • Board-Certified Specialist, Japan Society of Anti-Aging Medicine
  • Board-Certified Diagnostic Radiologist
  • Board-Certified Nuclear Medicine Physician
  • Member, Japanese Society for Regenerative Medicine
  • Member, Japan Society for Dementia Research

Publications & Academic Contributions

book

“Amazon #1 Bestseller”
Ranked #1 in 7 Medical Categories

  • starRanked No.1 Best Seller in the General Medicine Category
  • starRanked No.1 Best Seller in the Clinical Medicine Category
  • starRanked No.1 Best Seller in the Dermatology Category
  • starRanked No.1 New Release in the Medicine & Pharmacy Category
  • starRanked No.1 New Release in the General Medicine Category
  • starRanked No.1 New Release in the Clinical Medicine Category
  • starRanked No.1 New Release in the Dermatology Category

“Featured in The Wall Street Journal” Profiled for innovative patient-centered approaches Recognized as a leader in cellular therapy advancement

news

“Published Research & Clinical Impact”

PubMed
  • [First Author] Journal of Nuclear Medicine, 2022; 63:1919–1924
    Conducted a collaborative study with Pfizer Inc., pioneering the world’s first human use of a PDE4B-specific PET tracer.
    This groundbreaking research attracted international attention.
  • [First Author] ACS Chemical Neuroscience, 2020; 11:1311–1323
    Developed novel PET radiolabeled compounds for brain disorders, establishing a leading contribution in drug development and molecular imaging.
  • [Co–First Author (Equal Contribution)] Journal of Nuclear Medicine, 2020; 61:1672–1677
    Led a study identifying lesions in McCune–Albright syndrome, a rare and intractable disease, using PET imaging. Contributed as co-first author in advancing this research.
  • [First Author] Neurological Sciences, 2018; 39:1401–1407
    Conducted advanced neuroimaging analysis in Parkinson’s disease, proposing a novel quantitative imaging technique applicable to clinical practice.
  • [First Author] Kobe Journal of Medical Sciences, 2017; 62:136–141
    Discovered white-matter amyloid deposition in Alzheimer’s disease, providing key insights into disease pathology.
  • [Corresponding Author] Japanese Journal of Radiology, 2018; 36:519–527
    Comprehensively characterized imaging patterns of central nervous system complications following radiotherapy, reflecting extensive expertise as a diagnostic radiologist.

Stem Cell
Therapy

Autologous
Adipose-Derived

Adipose-Derived

Stem cells power your body’s natural repair system. As we age, these essential cells decline due to aging, disease, and stress—slowing recovery and accelerating visible signs of aging. Stem cell therapy replenishes your body’s regenerative capacity, restoring its natural ability to heal from within

How Stem Cell Therapy Works

How Stem Cell Therapy Works
How Stem Cell Therapy Works

What We Treat

  • Chronic Pain
  • Knee Osteoarthritis
  • Diabetes
  • Arteriosclerosis
  • AGA•FAGA
  • ED
  • Aged Skin
  • Age-Related Frailty
Premium Cell Cultivation × Premium Stem Cells
Premium Cell Cultivation × Premium Stem Cells
Top Quality
No Pre-Batching
Japan Top Quality

Your Treatment Journey

Your Treatment Journey

Heal Your Knees Without Surgery

Knee Regeneration
・Stem Cell Therapy・

Could This Be Your Solution?

  • Traditional treatments haven’t worked

    “Traditional treatments haven’t worked”Painkillers, injections, and physical therapy provided only temporary relief

  • Everyday activities have become painful

    “Everyday activities have become painful”Walking, climbing stairs, or simply standing feels challenging.

  • You want to avoid going under the knife

    “You want to avoid going under the knife”You’re looking for a proven alternative to surgery

Visible Cartilage Regeneration

Beyond Insulin: A New Path to Blood Sugar Control

Diabetes Regenerative Therapy
・Stem Cell Therapy・

  • Type 1 and Type 2 diabetes
  • Diabetes-related complications
  • Insufficient improvement with conventional treatments
How it work
Expected Benefits
Expected Benefits
 Healing Beyond Blood Sugar

Reference: Zhang Y., et al. Aging and Disease 2020

Science-Driven Age Reversal

Anti-aging
・Stem Cell Therapy・

Anti-aging icon
Menopausal Disorders

Menopausal Disorders

  • Restores hormonal balance
  • Supports ovarian and systemic function
  • Alleviates both physical and emotional symptoms associated
    with menopause
ED

ED

  • Promotes vascular regeneration and improves blood flow
  • Supports natural and long-lasting functional recovery
  • A new, drug-free therapeutic option
AGA / FAGA

AGA / FAGA

  • Directly revitalizes hair matrix cells within the scalp
  • Stimulates dormant follicles and promotes new hair growth
  • Rebuilds a healthy scalp environment for strong, resilient hair

Break Free from Chronic Pain
Chronic pain
・Stem Cell Therapy・

Chronic pain icon

Stem cells help reduce inflammation, improve blood circulation, and protect nerves
— supporting the natural repair of damaged tissues and helping enhance your quality of life.

Regenerate your vascular health
Arteriosclerosis
・Stem Cell Therapy・

Arteriosclerosis icon

Stem cell therapy works deep within your blood vessels, repairing damaged inner linings, reducing chronic inflammation, and restoring natural flexibility. By improving vascular function at the cellular level, this treatment helps prevent heart attacks and strokes while offering hope for those already living with cardiovascular disease.

Advanced Regenerative Skin TherapyPremium Dual-Cell Treatment

stem cells

Synergistic Effects of Dual-Cell Therapy

Fibroblasts stimulate collagen and elastin production deep in the dermis, while stem cells rejuvenate the entire skin environment—working together for dramatically enhanced results

Synergistic Effects of Dual-Cell Therapy

Stem Cell Culture Supernatant

Exosome

Stem cell culture supernatant contains no live cells, yet delivers therapeutic benefits comparable to traditional stem cell therapy.
This makes it a more accessible, cost-effective option and an ideal starting point for those new to regenerative medicine.

Treatment Benefits

  • Pain Relief
  • Joint Restoration
  • Hair Regrowth
  • Men's Intimate Wellness
  • Radiant Skin
  • Age Reversal

How Does It Compare to Stem Cell Therapy?

How Does It Compare to Stem Cell Therapy?

Science-Backed Safety, Clinically Proven Results

Where do the stem cells come from?

Healthy Japanese individuals through our partner medical facilities.

Where do the stem cells come from?

Serum-free without bovine or human serum. 
All sterility, mycoplasma, and other safety tests were negative

Where do the stem cells come from?

Different types of supernatant are chosen based on the treatment purpose

Different types of supernatant are chosen based on the treatment purpose
Different types of supernatant are chosen based on the treatment purpose

What are components?

Growth factors Cytokines
Exosomes

What sets our exosome therapy apart?

We use only the youngest, most potent stem cells (early passage) to ensure peak bioactivity. Each IV treatment delivers 300 billion exosomes

NKT
cell-based
immunotherapy

NKT icon

NK cells are immune cells that play a central role in the innate immune system.They act like “internal bodyguards,” quickly recognizing and eliminating harmful virus-infected cells and cancer cells.

NK cell
step

PRP
therapy

PRP icon

PRP therapy uses concentrated growth factors from your own blood to reduce inflammation and promote healing—the same treatment trusted by professional athletes for rapid recovery. Our Japan-made equipment ensures the highest quality, most concentrated PRP for optimal results.

step

Comprehensive Health
Blood Screening

Comprehensive Health icon
Teoria Cancer Screening

Detect pancreatic and gastrointestinal cancers at ultra-early stages through advanced exosome analysis—identifying threats long before traditional imaging can.

Ultra-Early Detection
EpiClock Genetic Test

A genetic test that measures your biological age and the speed of aging.

EpiClock Genetic Test
EpiClock Genetic Test

NMN
Therapy
Activate sirtuin genes and
mitochondrial function

NMN icon

Maximum Bioavailability

Patented nanoPDS® technology delivers 3-4× higher absorption than conventional NMN, ensuring optimal cellular uptake and effectiveness

Pharmaceutical-Grade Purity

Formulated with naturally derived β-NMN produced through Japan-made fermentation and cultivation methods.

Verified by absolute quantitative analysis, ensuring a genuine purity of 99.91%.

nanoPDS®

Clinically Proven Safety

N-Pro Med™ is the only NMN IV formulation clinically proven safe and effective for human use—backed by rigorous scientific validation.
Clinical studies have demonstrated NMN’s potential to reduce blood triglyceride levels and support overall metabolic health.

N-Pro Med™
CELL GRAND CLINIC

4F, Midosuji Minami Building (FENDI Building), 2-3-2 Nishishinsaibashi, Chuo-ku, Osaka 542-0086, Japan

TEL 06-6212-5960

TEL 06-6212-5960

MAIL info@cellgrandclinic.com

map
  • Osaka Metro Midosuji Line – 5-minute walk from Shinsaibashi Station (Exit 7)
  • Osaka Metro Midosuji Line – 5-minute walk from Namba Station (Exit 25)
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